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Pradaxa And Renal Functioning

Submitted by • September 25, 2012

The concentrations of Pradaxa found in those patients who took part in the RE-LY study increased as much as 30% in those over the age of 75 as compared to those aged 65-75 and was 68% higher than those younger than 65. Since the anticoagulation effect of Pradaxa is definitely dose dependent, it is believed that any type of kidney dysfunction along with advanced age while not actually causing bleeding events could definitely exacerbate them. The gastrointestinal bleeding found in the lower GI tract is believed to be definitively tied to the Pradaxa delivery method as it moves through the digestive tract.

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